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What is the value of renal function tests on PKU and diabetic patients?
Alexiacoward
Renal function tests are an easier way of checking for potential brain damage; if phenylalanine and glucose aren't metabolized effectively by the kidneys, it can effect cellular interactions - the glucose and phenylpyruvic acid (metabolite of phenylalanine in PKU patients) can accumulate in the spine, which can lead to permanent nerve damage and, in severe cases, poly-arthrocitic brain tumours.
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∙ 13y ago
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