A three letter word for gender is sex.
ton
The 8-letter "opposite gender" of a male giant is "giantess." (There is no common 8-letter antonym to a giant or to the adjective giant.)
The opposite gender for paper is masculine, so it would be referred to as "he".
nix
all
LED
war
dim
The word drank does not have a gender
There is no opposite gender for the noun 'misdeed'. The noun misdeed is a neuter noun, a word with no gender.
ILL ?