Mitotic marker, that when injected will show cells that are entering the S-phase, or proliferating stage of mitosis.
Thymidine birthdating is a method used to determine the age of cells in the body. It involves labeling dividing cells with a chemical called thymidine analog, which gets incorporated into the DNA of newly formed cells. By analyzing the presence and distribution of these labeled cells, researchers can estimate when the cells were generated, providing insights into cellular turnover rates and tissue regeneration.
Double Stranded DNA is paired, with Adenine paired with Thymine Cytosine paired with Guanine Then the percent Cytosine in one strand will be exactly the percent Guanine in the other strand. And between the two strands, the percent Cytosine will be equal to the percent Guanine. For a random distribution, the percent should be about 25% for each nucleotide, or 50% for the GC pair, and 50% for the AT pair. However, DNA actually varies considerably from organism to organism. Streptomyces coelicolor A3(2), has a GC content as high as 72% Plasmodium falciparum has a GC content as low as 20%. See Wikipedia link on GC Content.
Short Answer: A,T,C,GLong Answer: Each nucleotide has 3 basic parts, all connected together into a single molecule.The 3 parts are a phosphate, a sugar and a base.All four monomers have the same deoxyribose (a five carbon sugar) and a phosphate group(PO4). Each nucleotide is distinguished by their different bases.Bases: Adenine (A), Cytosine (C), Guanine (G), and Thymidine (T).
If by "four chemicals" you mean nucleotides, then they are as follows: 1. deoxyadenosine monophosphate or adenine 2. deoxyguanosine monophosphate or guanine 3. deoxycytosine monophosphate or cytidine 4. deoxythymine monophosphate or thymidine The chemical bonds holding DNA molecules together are 1. phosphodiester bond in the polynucleotide strand 2. hydrogen bond between the complementary nitrogenous bases on adjacent polynucleotide strands.
Helicases must break the hydrogen bonds between paired nucleotide bases (Thymidine-Adenosine or Guanosine-Cytosine) of DNA strands so the two strands can be separated and replicated. The origins of replication, the initial "replication bubbles", tend to be in sequences that are A-T rich because Adenine-Thymidine has only two hydrogen bonds, energetically easier for helicases to start breaking than the three hydrogen bonds between Guanosine-Cytosine. For replication to continue topoisomerases must also cut the phosphate backbones of DNA strands, otherwise the helically wrapped strands would get much too overwound or "supercoiled" for polymerases and related replication machinery to continue to function. Nucleosomes (complexes of histone proteins that DNA wraps around) also have to be rearranged or removed to allow for replication.
That depends on how big your DNA is. Given that there are 10 carbons each per adenosine, guanosine, and thymidine and 9 carbons per cytidine.... which means there are 20 carbons per A-T basepair, and 19 carbons per G-C basepair... assuming the genome is 50% GC, that would mean an average of 19.5 carbons per base pair. The human genome is roughly 3 billion basepairs long... so I'd estimate in round numbers that there are about 58.5 billion carbon atoms in the genomic DNA of a single human cell.
Thymidine is a nucleoside that consists of one thymine molecule linked to a d-doxyribose sugar molecule. Radioactive thymidine is usually used in DNA labeling.
Thymidine- a nucleoside component of DNA; composed of thymidine and deoxyribose
Thymidine.
C10H14N2O5
Thymidine
Thymidine
J. E. Cleaver has written: 'Thymidine metabolism and cell kinetics' -- subject(s): Cell populations, Radioactive tracers in cytology, Thymidine metabolism
TGG
The Nucleosies: guanosine, adenosine, thymidine and uridine?
In DNA replication A (adenosine) binds to T (thymidine).
Paul Mullan has written: 'Changes in thymidine metabolism during induced differentiation in leukaemia'
Acyclovir can help treat herpes. The herpes's simplex virus thymidine kinase can phosphorylate the drug into its monophosphate. As it is a poor substrate for the thymidine kinase of humans, it is not toxic for non-infected cells. This drug competes with dGTP as a competitive inhibitor. Once is enters the DNA, it can act as a chain terminator.