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Vasular Endothelial Growth Factor, or VEGF, is a signaling protein that is involved in the formation of the embryonic circulatory system and the growth of blood vessel from those that already exist.
VEGF has been associated with poor prognosis in breast cancer, making anti-VEGF treatments important in the treatment of Breast cancer.
What else can I help you with?
How do you know if you have vascular endothelial growth factor-antisense oligonucleotide?
by the time you find out it's too late because it is in fact lethal
What has the author Paraskevi Sisi written?
Paraskevi Sisi has written: 'Investigation of the role of vascular endothelial growth factor in the process of cervical ripening during parturition'
What is the role of vascular endothelial growth factor (VEGF) basic fibroblast growth factor (bFGF) and transforming growth factor-alpha (TGF- and alpha) in cell metastasis?
Vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF), and transforming growth factor-alpha (TGF-α) play crucial roles in cell metastasis by promoting angiogenesis, cell proliferation, and tumor microenvironment modulation. VEGF facilitates the formation of new blood vessels, supplying nutrients to tumor cells and enabling their spread. bFGF enhances cell migration and proliferation, contributing to tumor growth and invasion. TGF-α can stimulate epithelial-to-mesenchymal transition (EMT), a process that increases the metastatic potential of cancer cells by promoting their invasive characteristics.
What biochemical is important in glomerulus formation in the embryo?
Vascular endothelial growth factor (VEGF) is important in glomerulus formation in the embryo. It promotes the development and maintenance of blood vessels, including those in the kidney that form the glomeruli.
Can anemia lead to oedema?
anemia causes increased production of vascular endothelial relaxing factor that causes dilatation of the vasculature producing oedema.
What are the key growth factors involved in the process of wound healing?
The key growth factors involved in wound healing are proteins that help stimulate cell growth and repair, such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-beta), and vascular endothelial growth factor (VEGF). These growth factors play a crucial role in promoting the formation of new blood vessels, collagen production, and tissue regeneration, ultimately aiding in the healing process.
What pathologies are associated with endothelial cell dysfunction?
Thrombosis, atherosclerosis, and hypertensive vascular lesions.
What has the author Shauna M Dauphinee written?
Shauna M. Dauphinee has written: 'Endothelial dysfunction and inflammation' -- subject(s): Diseases, Physiopathology, Vascular endothelium, Pathophysiology, Inflammation, Pathology, Endothelial Cells, Vascular Endothelium, Cardiovascular system
What has the author Andrew Bryan Sutton written?
Andrew Bryan Sutton has written: 'The response of endothelial cells and pericytes to transforming growth factor beta'
What are the 2 main types of cell tissues in the vascular system?
The two main types of cell tissues in the vascular system are endothelial tissue and smooth muscle tissue. Endothelial tissue lines the interior of blood vessels, providing a barrier and playing a crucial role in regulating blood flow and vascular permeability. Smooth muscle tissue surrounds the endothelial layer, allowing for the contraction and relaxation of blood vessels, which helps regulate blood pressure and flow. Together, these tissues work to maintain vascular health and function.
What is the beginning of the extrinsic pathway of coagulation?
The extrinsic pathway of coagulation is initiated when tissue factor (TF), which is released from damaged endothelial cells and tissues, binds to factor VII. This complex activates factor VII to factor VIIa, which then catalyzes the activation of factor X to Xa. This pathway is crucial for rapid hemostasis and is typically activated in response to vascular injury.
How does angiogenesis work?
In low oxygen gene regulatory protein called HIF-1 stimulates the transcription of the VEGF gene, the Vascular endothelial growth factor. This causes the endothelial cells to use proteases to digest there way through and bring new blood to the cells. This can also happen in cancers cells and this how cancer tumors can become vascularized. In a disorder called VHL - Von hippel-lindau. They are only born with one functioning copy of the VHL gene, mutations occur and they get random cancer throughout there body.
