The Letter U is missing because it is spelled instead as "you"
I
Q
I
E dEsEr....E
a
d
S
The letter is L and the number is 12.
The missing letter is C. When the alphabets are used to represent the missing space, the sequence becomes "A B C D E F G H I J K L M N O P."
You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.You are nearly correct. You are missing the letter e in the middle. It is noticeable.
The letter "e" completes the sequence.
The next letter in the sequence is S. The sequence follows the pattern of skipping every other letter in the alphabet, starting with C.