They opened up their trade centers
The flag at Fort Sumter was lowered by Major Robert Anderson when he surrendered the fort. This was in April of 1861.
Lassic happened in 1861.
One of the biggest events would be the Civil War starting out. Just type in what happened in 1861 on google and follow the wikipedia link.
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The Civil War
It occurred on April 1861.
Yavapai Wars happened in 1861.
Siege of Saigon happened in 1861.
Union blockade happened in 1861.
Battle of Pavón happened in 1861.
Bezdna Unrest happened in 1861.
Bascom Affair happened in 1861.