I'm not sure what counts as a "medieval word". I assume that you are asking about an English word, not French or German or Italian or Greek, although these languages also existed in medieval Europe. I also assume you don't want a Latin word, although Latin was an important part of medieval culture everywhere, being the language of the Catholic Church. The word "medieval" can imply just about any time between 450 A.D. and 1500 A.D., over 1000 years. Over those 1000 years English changed so much it became a totally different language. Nevertheless, many of the English words from that time are English words today. Are you looking for a word which was a word then but is not now? Let us look then at a text written in 1380, Chaucer's Canterbury Tales. Here in the general prologue we find words like Of, On, Or, Onto, Over, Out, Oath (spelled ooth), One (spelled oon), Old, Oyster (spelled oistre), Order (ordre), Office (offyce) and Overest. Overest? It comes from the description of the Clerk: "Ful threadbare was his overest courtepy." A courtepy was a short cloak, which he wore over everything else; "overest" means on top of everything else or uppermost.
orchestrate is an active word that begins with the letter O
it begins with the letter o. but if you are french, it begins with a letter o.
One-half is a hyphenated word. It begins with the letter O.
onlyonceomenopenomitoverontoovidovum
overdo
Bombs are overpowering and destructive. The adjective begins with the letter O.
off
Outstanding is a nice word. It begins with the letter O.
Outside?
Offensive is a synonym for horrible. It begins with the letter O.
The word is onslaught.
· Organ