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How can someone with sickle cell survive a malarial infection?
Yes. Because of the structure of hemoglobin in a patient with sickle cell anemia, malarial parasites that attempt to infect red blood cells cause the red blood cell to burst before it can be infected, effectively starving the parasite of a host. Since the allele for sickle cell anemia is codominant with the allele for regular hemglobin, sometimes people whose parents have sickle cell can pass on their resistance to malaria to their children without passing on the entire disease for sickle cell.
If sickle-cell anemia is so destructive why hasn't the sickle-cell allele been eliminated from the population?
It is important to note that sickle-cell anemia comes in two forms. The homozygous sickle-cell anemia and the heterozygous sickle-cell trait. The difference between the two is that sickle-cell anemia has a high rate death rate at a young age (20~), and the sickle-cell trait is nearly asymptomatic.In regions such as North America, sickle-cell anemia would be selected against and would eventually leave the gene pool. The sickle-cell trait on the other hand, has little effect on the fitness of the organism, and as such will remain in the gene pool.In malaria endemic regions such as sub-Sahara Africa, sickle-cell anemia provides very high levels of immunity to malaria and the sickle-cell trait provides a slightly lesser level of immunity. Both forms of sickle-cell will increase the organisms fitness and as such, it will remain in the gene pool. Further on, the sickle-cell trait has greater fitness than sickle-cell anemia, hence, the sickle-cell trait will be selected as the fittest allele.If s is the sickle-cell allele and S is a normal allele;The relative fitness in malaria endemic regions;Ss > ss > SSSickle-cell trait > Sickle-cell anemia > NormalThe relative fitness in non-malaria endemic regions;SS > Ss > ssNormal > Sickle-cell trait > Sickle-cell anemia
Why is sickle cell called a sickle cell?
The shape of the cell is misshapen.
What is sickle cell in white people called?
Sickle Cell....... My son has been diagnosed with sickle cell trait. We are white and the doctors called it Sickle Cell Trait! hope this helps...
What is the sickle cell trait of sickle cell anemia?
The sickle cell trait is that you dont have the whole thing you have half of it which is called the trait
Is sickle cell anemia a point mutation?
An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.
Is sickle cell anemia the same as sickle cell diseases?
yes
Is the fetus at risk of sickle cell if the father has sickle cell?
Yes.
Can child be born with sickle cell if one parent is sickle cell carrier and another is normal?
A child has to receive the gene from both parents to heve sickle cell anemia. if only one parent passes on the gene, then the child will have sickle cell trait, but no symptoms of sickle cell anemia.
Sickle-cell anemia is an example of a point-mutation?
An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.
What genetic disorder results in abnormally shaped blood?
Spherocytosis
What are other names for sickle cell anemia?
Hemoglobin SS disease (Hb SS)
