It can affect any joint from the jaw, neck, shoulders, elbows, wrists, hands, fingers, lower back (ankylosing spondylitis), hips, groin, knees, ankles, feet and toes. In severe cases it can also cause inflammation throughout the body such as inflammation of the body surrounding the heart and lungs. Along with inflamation, swelling and pain there are many secondary and complications of RA. Some fo these include disease such as Raynoud's- a connective tissue disease dealing with lack of circulation.
Usually the joints, However it can also attack organs and tissue like the lungs eyes, heart bones muscles and epidermis
Rheumatoid arthritis. This disease is the result of the immune system mistakenly turning on its own body and destroying connective tissu such as cartilage. It can also affect many other parts of the body.
Rheumatoid arthritis is an autoimmune disease that effects the joints of the body and other parts of the body with connective tissue What happens is the umune system mistakenly rejects the body's tissue leading to damage.
Rheumatoid comes from the term "rheuma" which meaning "a substance that flows". Upuntil the 1800's rheumatoid arthritis, was thought to be caused when "humours", substances that were thought to flow through the body stopped in certain parts of our body, such as joints in the case of arthritis,(Arthritis, from Greek arthro-, joint + -itis, inflammation) bringing about pain and swelling.
The joints in your body
This would refer to the type of arthritis that tends to affect the same joints on both sides of the body at the same time, there is a symmetry to the way it flares and is generally Rheumatoid arthritis.
My guess is that you read the term for seronagative Rheumatoid arthritis. Rheumatoid arthritis is a immune disorder that usually exhibits itself in several joints of the body at the same time, (often the same joints on opposite sides of the body). When it is suspected that Rheumatoid arthritis is the culprit one of the blood tests that is done is one for Rheumatoid factor (RF) most of the people that have RA also have a high RF, However in about 20% of cases there is no RF and this is Known as seronegative Rheumatoid arthritis.
It is not unusual for Anemia or "low blood" to accompany rheumatoid arthritis. Anemia indicates a low number of red blood cells and that these cells are low in hemoglobin, the substance that carries oxygen through the body. A low white blood cell count (leukopenia) can occur as a result of Felty's syndrome which is a complication of rheumatoid arthritis that is also characterized by enlargement of the spleen.
Rheumatoid arthritis is in itself not a fatal disease, however life expectancy is often a little shorter shorter for people with RA. This does not necessarily apply to all that have RA however as there can be many organs affected, many complications and treatment related side effects can contribute to premature death.Rheumatoid arthritis usually affects the joints, never the less it is a condition that can effect and impact on entire body. Rheumatoid arthritis is a systemic disease that can affect many of the body's organs and normal functions..
The imune system
Usually stiff sore or swollen joints are a pretty good indicator. However with forms of arthritis like Rheumatoid arthritis which is an Autoimmune disease other parts of the body may be effected.
Yes Rheumatoid arthritis is an immune system disorder in which the immune system turns on the body and mistakenly destroys tissue.
Rheumatoid arthritis nodules can appear any where on your body however I have not been able to find reference to the palm of the hand.