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InterphaseBefore a cell can enter cell division, it needs to prepare itself by replicating its genetic information and all of the organelles. All of the preparations are done during the interphase. Interphase proceeds in three stages, G1, S, and G2. Cell division operates in a cycle. Therefore, interphase is preceded by the previous cycle of mitosis and cytokenesis.

[Diagram showing the cell cycle. The size of the arrows show the relative length of each stage of the cell cycle. Notice mitosis (M) is quite short.]

G1 Phase

After mitosis is complete the new daughter cell begins to accelerate its biochemical processes which were slowed down by mitosis. The length of the G1 phase creates the difference between fast dividing cells and slowly dividing cells. The G1 phase can be slowed by reducing the nutrients available in a system - thus the cell will take longer to build up the resources necessary for cell division. If there is a severe depletion in nutrients the cells can virtually stop growing. It is interesting to note that cells that aren't growing are always stopped in the G1 phase, being mitotically arrested. This suggests that once the cell enters the S phase, it is committed to cell division, regardless of the external cell conditions.

[Animal cell interphase. The DNA has been replicated. Also, notice the increased cell size as the cytoplasm has been enlarged.]

S Phase

The S phase begins with the replication of the cellular DNA. This is described in further detail in DNA replication. When the cellular DNA has been duplicated, leaving the cell with twice as many chromosomes (each chromosome is made up of two identical chromatids), the cell moves onto the G2 phase.

G2 Phase

During this phase proteins, such as kinase (which catalyzes protein phosphorylation), which are necessary for cell division are synthesized at this time. The chromosome begins to condense and the proteins necessary for construction of the mitotic spindle also are synthesized. When the chromosomes become visible the cell enters the first stage of mitosis, prophase.

Continue on to Mitosis 1: Prophase

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Emiliano Torp

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Related Questions

During which phase of mitosis do the chromosomes form?

The chromosomes form during the prophase of mitosis. In prophase, the chromatin condenses into visible chromosomes as the nuclear envelope breaks down, allowing the chromosomes to be organized and prepared for segregation into daughter cells.


What two phases of mitosis can chromosomes be seen?

Chromosomes can be distinctly seen during the prophase and metaphase of mitosis. In prophase, chromatin condenses into visible chromosomes, each consisting of two sister chromatids joined at the centromere. During metaphase, the chromosomes align at the cell's equatorial plane, making them easily observable under a microscope.


Doubled chromosomes first become visile in which step of mitosis?

double chromosomes first become visible in which step of mitosis?


What are the four active phases of mitosis?

The four active phases of mitosis are prophase, metaphase, anaphase, and telophase. During prophase, the nuclear membrane dissolves, and chromatin condenses into visible chromosomes. In metaphase, the chromosomes align along the cell’s equator. Anaphase involves the separation of sister chromatids to opposite poles. Telophase marks the reformation of nuclear envelopes and the decondensation of chromosomes.


When does a chromosome first become visible in mitosis?

During the Prophase. :)Chromosomes become highly condensed.They are visible to light microscope,not naked eye


When choromosomes are visible in the nucleus?

Chromosomes are visible in the cell nucleus during mitosis and meiosis.


When during the cell cycle are chromotomes visible?

Chromosomes are visible during cell division, specifically during mitosis and meiosis. This is when the chromosomes condense and become more distinguishable. In interphase, the chromosomes are less condensed and not easily visible as individual structures.


Chromosomes first become visible during which phase of mitosis?

They first become visible during prophase of mitosis.


Are dyads visible in mitosis?

No, dyads are not visible in mitosis. Dyads are two sister chromatids joined at the centromere, and they separate during anaphase of mitosis to form individual chromosomes that are visible under a microscope.


When is the genetic material visible in a cell?

DNA is visible during mitosis (replication) when the chromosomes condense.


What is the first clue that mitoosis has begun?

The first clue that mitosis has begun is the condensation of genetic material into visible chromosomes. This occurs during the prophase stage of mitosis when the chromosomes become visible under a microscope.


What phases are chromosomes not visible?

Interphase and Telophase