Urine is usually collected throughout a 24-hour time period. A person is given a large container in which to collect the urine. The urine should be refrigerated until it is brought to the laboratory or physician's office.
Normal results for a Bence Jones protein test should show no detectable levels of Bence Jones protein in the urine, indicating a healthy kidney function and no abnormal protein excretion. If Bence Jones protein is present in the urine, further investigation may be needed to determine the underlying cause.
The Bence Jones protein is a type of monoclonal immunoglobulin light chain that is found in the blood or urine of patients with multiple myeloma, a type of blood cancer that affects plasma cells in the bone marrow. The presence of Bence Jones protein in the urine, known as Bence Jones proteinuria, is a key diagnostic marker for multiple myeloma. Detection of Bence Jones protein in the blood or urine can also indicate other conditions such as Waldenström macroglobulinemia or amyloidosis.
The best specimen for a Bence Jones protein test is a 24-hour urine sample. This allows for the most accurate measurement of protein excretion over a full day, which is important for detecting and monitoring conditions such as multiple myeloma.
Protein Electophoreis, serum and Urine. It reveals Bence Jones Protein.
.Multiple myeloma, a tumor of plasma cells, is the disease most often linked with Bence Jones proteins.Physicians use Bence Jones proteins testing to diagnose the disease as well as to check how well the disease is responding to treatment.
Patients with plasmacytomas such as myeloma overproduce monoclonal immunoglobulins, also called M proteins. The Bence-Jones protein refers to the immunoglobulin light chain, a portion of these immunoglobulins.
heat and acetic acid test
Henry Bence Jones died in 1873.
Henry Bence Jones was born in 1813.
Heat test for Bence-Jones protein involves heating a urine sample to 60-100°C for 5 minutes, followed by observation for the presence of precipitate. A positive test results in the formation of a gelatinous or flocculent precipitate, indicating the presence of Bence-Jones protein. This test is commonly used to screen for multiple myeloma.
Bence Jones proteins are small proteins (light chains of immunoblobulin) found in the urine. Testing for these proteins is done to diagnose and monitor multiple myeloma and other similar diseases.
put 5ml of concentrated hydrochloric acid in a clear tube.carefully add 3ml of test urine to make a good interface without mixing the two.a white curdy precipitate at the interface indicates presence of bence Jones protein