he got lost
On problem Christopher Columbus faced was sickness. He faced harsh weather, as well as violent people who did not know who he was or what he was about.
Columbus did indeed use a compass on his voyages; the compass (lodestone in its earliest incarnation) is arguably the oldest known navigational instrument. The problem is that compasses point to Magnetic North, not True North. Because of this, course errors are induced, and the degree and angle of error will change as position changes
Actually Spain and Portugal wanted the lands Christopher Columbus discovered and would even fight for it. Later Pope Alexander VI settled the problem by making a boundary for Spain and Portugal.
Christopher Columbus sought to find a westward route to Asia to facilitate trade, particularly for valuable goods like spices and silk. At the time, European trade with Asia was primarily conducted overland or via established sea routes that were long and perilous. Columbus aimed to bypass these routes, thereby reducing travel time and costs, and ultimately increasing European access to lucrative markets. His expeditions inadvertently led to the discovery of the Americas, reshaping global trade and exploration.
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Yes, the trip was very dangerous - the crew faced storms, calm seas (a major problem when you rely on the wind to move you forward), disease, short rations and almost mutiny.
what disease or problems we encounter without the special functions of the bones