Stump, P. R., R. Baccarelli, L. H. Marciano, et al. "Neuropathic Pain in Leprosy Patients." International Journal of Leprosy and Other Mycobacterial Diseases 72 (June 2004): 134-148.
Patients with MB leprosy are usually treated with all three drugs, while patients with PB leprosy are only given rifampin and dapsone.
In patients with LL leprosy, the bacilli are easily detected.
Some physicians have advocated dapsone treatment for people in close household contact with leprosy patients.
Buschman, E., and E. Skamene. "Linkage of Leprosy Susceptibility to Parkinson's Disease Genes." International Journal of Leprosy and Other Mycobacterial Diseases 72 (June 2004): 169-170.
Although patients with leprosy are commonly thought not to suffer pain, neuroapthic pain caused by inflammation of peripheral nerve endings is increasingly recognized as a major complication of the disease in many patients.
Meima, A., W. C. Smith, G. J. van Oortmarssen, et al. "The Future Incidence of Leprosy: A Scenario Analysis." Bulletin of the World Health Organization 82 (May 2004): 373-380.
Ulcers in the feet of leprosy patients primarily result from nerve damage caused by the disease, which leads to loss of sensation. This insensitivity makes individuals unaware of injuries or pressure on their feet, allowing wounds to develop and worsen without proper care. Additionally, poor circulation and immune response in these patients can impede healing, further contributing to the formation of ulcers. Regular foot care and monitoring are essential to prevent complications in leprosy patients.
Corticosteroids may be given to reduce the inflammation.
The Tichilesti leprosy was founded in 1875; now are only approx. 20 patients - they are not dangerous or contagious but they prefer to remain here. The last case of leper in Romania is from 1981. The decision is from sanitary authorities.
Leprosy patients should be aware that treatment itself can cause a potentially serious immune system response called a lepra reaction.
Physiotherapy exercises are taught to the patients to maintain a range of movement in finger joints and prevent the deformities from worsening.
One of the hallmarks of leprosy is the presence of AFB in smears taken from the skin lesions, nasal scrapings, or tissue secretions.