Your grandson is your brother-in-law's great nephew, and your brother-in-law is your grandson's great uncle.
Your grandson and your brother's grandson are second cousins to each other.
Your niece's grandson is are your great-grandnephew.
Your first cousin's grandson son is your grandson's third cousin. Your second cousin's grandson is your grandson's fourth cousin. Etc., etc.
Your sister would be your grandson's great aunt.
Your sister is your grandson's great aunt. He is her great nephew.
Your great aunt's grandson is your second cousin.
You Aunt is you grandson's Great-Great Aunt. Your grandson is your Aunt's Great-Great Nephew.
Your grand niece and your grandson are second cousins to each other
Your sister's child and your grandson are first cousins once removed.
Your grandson and your first cousin are first cousins, twice removed.
Second cousins.
Nephew?!