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Pallidotomy is major surgery on the brain. It may cause excessive bleeding, and care must be taken in patients susceptible to uncontrolled bleeding or who are on anticoagulant therapy.

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When is a unilateral pallidotomy suggested?

Unilateral (one-sided) pallidotomy may be used if symptoms are markedly worse on one side or the other, or if the risks from bilateral (two-sided) pallidotomy are judged to be too great.


What should a candidate for a pallidotomy discuss with her doctor prior to surgery?

The surgical candidate should discuss all the surgical options with the neurologist before deciding on pallidotomy. A full understanding of the risks and potential benefits must be understood before consenting to the surgery.


What factor reduces the risks involved in undergoing a pallidotomy?

While there are several controversies in the field of PD surgery, all experts agree that risks are reduced in procedures performed by the most experienced neurosurgeons.


What specialist performs the pallidotomy?

Pallidotomy is performed in the hospital by a neurosurgeon, in coordination with the patient's neurologist.


What is a basic difference between the unilateral and bilateral pallidotomy?

For unilateral pallidotomy, a single "burr hole" is made in the top of the skull; bilateral pallidotomy requires two holes.


How does the pallidotomy procedure mimic the effect of dopamine?

Pallidotomy mimics this action by permanently destroying the GPi cells.


What is key to a successful outcome of a pallidotomy?

The key to successful outcome in pallidotomy is extremely precise placement of the electrode.


What does a pallidotomy do?

In a pallidotomy, the globus pallidus is destroyed by heat, delivered by long thin needles inserted under anesthesia


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What additional step is necessary in a bilateral pallidotomy?

If bilateral pallidotomy is being performed, the localizing and lesioning will be repeated on the other side.


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