If you refer to the Great Lakes of North America then the answer is the St Lawrence Seaway.
No body of water separates the US. from Mexico
The Pacific Ocean separates Asia and California, The Arctic Ocean separates Alaska from northern Asia.
The Ocean that separates Africa and America is called the Atlantic Ocean. It is the second largest ocean, behind the Pacific Ocean.
There are several geographic features that separate two ecozones. These may be the alps, oceans, deserts, or even seas.
The ocean that separates North America and Europe is the Atlantic Ocean.
The ocean that separates Africa and Europe is the Mediterranean Sea.
The North Atlantic Ocean separates North America from Europe.
The Atlantic Ocean .
Atlantic Ocean
The Pacific Ocean.
Atlantic Ocean.
The Atlantic.