That would depend on which model YEAR , and if you mean which of the
several sizes of gasoline engines available , or if you mean a diesel engine
A little more detail please
The 2014 Ford F-250-Super-DUTY has a V8 engine.
The 2002 Ford F-250-Super-DUTY has a V8 engine.
The 2013 Ford F-250-Super-DUTY has a V8 engine.
The 2004 Ford F-250-Super-DUTY has a V8 engine.
The 2008 Ford F-250-Super-DUTY has a V8 engine.
The 2005 Ford F-250-Super-DUTY has a V8 engine.
The 2006 Ford F-250-Super-DUTY has a V8 engine.
The 2003 Ford F-250-Super-DUTY has a V8 engine.
The 2010 Ford F-250-Super-DUTY has a V8 engine.
The 2001 Ford F-250-Super-DUTY has a V8 engine.
The 2009 Ford F-250-Super-DUTY has a V8 engine.
The 2012 Ford F-250-Super-DUTY has a V8 engine.