There is no such thing as the letter 'you'.
A letter that starts with U is an urgent letter.
letter that starts with u is unicorne
Europe, Egypt,
undertaker
unique
A six letter word that starts with U is upward.
The Ukulele starts with the letter U.
Union Station starts with U.
The Libyan desert
No river in India starts with the letter U.
A tool that starts with U is a utility knife.
Ahmose