Santa Fe, New Mexico
"21 degrees north" is the description of a parallel of latitude that circles the earth, about 1,450 miles north of the equator. "106 degrees south" is a meaningless phrase. The greatest possible latitude is 90 degrees. The north pole is 90 degrees north, while the south pole is 90 degrees south.
That puts you in the Bay of Biscay, about 106 miles north of Santander (Spain) and 167 miles west of Bordeaux (France).
Russia
The city located at 6 degrees south latitude and 106 degrees west longitude is Lima, the capital of Peru.
The coordinates 34°N and 106°W correspond to the state of New Mexico in the United States. Latitude is measured in degrees north or south of the equator, and longitude is measured in degrees east or west of the Prime Meridian. By pinpointing these coordinates, we can accurately determine the location of a specific place on Earth's surface.
This point is not quite within a city's limits. The closest major city to this point is Phoenix, Arizona.
In Madrid that's the answer
That point is about 59 miles west-northwest of the city center of Jakarta, Indonesia.
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The Central Siberian Plateau, Russia.
There's no significant city there. That point is located in south-central China, about 50 miles southwest of the center of Chongqing.