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West Virginia is North-West of Virgina. They are adjoining states; West Virginia was once part of Virginia.
West Virginia is bordered by Ohio to the northwest.
West Virginia is north and a bit west from South Carolina.
It basically just depends where you are located. You can enter West Virginia in any direction.
You would travel west.
Moving from West Virginia to South Carolina you are traveling south. There are about 421 miles between South Carolina and West Virginia.
East
If you travel straight north from most parts of South Carolina, you would eventually cross into West Virginia. From the easternmost parts of South Carolina, you would have to go north and a bit west to get into West Virginia.
south Greenwich to West Vieginia is. 74° West of true North. West Virginia to Greenwich is, 48° East of true North.
East
East.
east