The simplest way would be to take the Downtown A-C-E (the blue line) from 34th Street-Penn Station to Canal Street.
You will exit the subway at the north end of the Tribeca neighborhood, just south of SoHo, at the intersection of Canal and Varick Streets. Walk one block north on Varick to Grand Street.
If you're going further east on Grand Street, then take the Uptown A or C (not the E) to 59th Street-Columbus Circle. Then transfer at 59th Street-Columbus Circle to the Downtown B or D trains (of the B-D-F-M, the orange line). Take the Downtown B or D to Grand Street (at Chrystie Street), which is in Chinatown.
To travel from Penn Station to 851 Grand Concourse in the Bronx, take the 2 subway line from 34th Street-Penn Station station towards Wakefield-241st Street. Transfer at the 149th Street-Grand Concourse station to the 4 or 5 line, and then continue to the 167th Street station. From there, it's a short walk to your destination at 851 Grand Concourse.
To get from Penn Station to 622 Third Avenue, you can take the 1, 2, or 3 subway lines from 34th Street-Penn Station to Times Square-42nd Street. From there, transfer to the 7 train and head to Grand Central-42nd Street. Once at Grand Central, it's a short walk to 622 Third Avenue.
To get from Penn Station to Worth Street, you can take the 1 subway line. Board the 1 train at 34th Street-Penn Station and travel downtown. Get off at the Chambers Street station, which is close to Worth Street. Alternatively, you could take the A or C train from 34th Street-Penn Station to Chambers Street for a similar route.
There is no train that runs directly between Penn Station and Grand Central. You have to take the subway: the Uptown 1-2-3(the red line), 1 stop, from 34th Street-Penn Station to 42nd Street-Times Square, then transfer to the S shuttle train (color grey) to 42nd Street-Grand Central.Trains on the New York City subway system operate continuously. There are schedules you can download, but they're often inaccurate.
No, but it does stop at penn station and you can take the subway
No, the AirTrain takes you to and from the subway, and the subway takes you to and from Penn Station. Take the AirTrain to the Howard Beach Station, and get the Manhattan-bound A train (of the A-C-E, the blue line) to 34th Street-Penn Station.
To get from Penn Station to 11 Broadway, take the 1, 2, or 3 subway lines from 34th Street-Penn Station. Travel downtown and get off at the Chambers Street station. From there, it's a short walk to 11 Broadway. Alternatively, you can also take the A or C train from 34th Street to Chambers Street.
To travel from LaGuardia Airport to Penn Station using the subway, you can take the M60 bus from the airport to the Astoria Blvd subway station. From there, you can transfer to the N or W train and take it to 34th Street-Herald Square station, which is near Penn Station.
To get to the Hayden Planetarium from Penn Station, take the A, C, or E subway line from 34th Street-Penn Station. Transfer at 42nd Street-Port Authority Bus Terminal to the 1 subway line, then travel uptown to 79th Street. From there, it's a short walk to the American Museum of Natural History, where the Hayden Planetarium is located.
To get from Grand Central Terminal to Penn Station, you can take the subway. Board the 7 train from Grand Central to Times Square-42nd Street, then transfer to the 1, 2, or 3 trains heading downtown and get off at Penn Station. Alternatively, you can walk, which takes about 20-30 minutes.
No, they are two separate train stations, located in two different places. New York City's Penn Station (there are other Penn Stations in the U.S.) is located at West 33rd to 34th Street, between 7th and 8th Avenues. Grand Central Station and Terminal is located at East 42nd Street between Park and Lexington Avenues. Grand Central Station is the subway station, where you can get the 4-5-6 (the dark green line), the 7 (the purple line) or the S shuttle train to Times Square. Grand Central Terminal is the railroad terminal for non-subway trains running in and out of New York City.
Take the Downtown 2 or 3 trains (of the 1-2-3, the red line) from 34th Street-Penn Station to Wall Street (at William Street).