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How are MALT lymphomas recognized in an endoscopy examination of the stomach?
MALT lymphomas are then recognized as areas of inflammation or ulceration within the stomach.
What causes MALT lymphomas outside the stomach?
It is not known if infectious agents also cause MALT lymphomas outside of the stomach.
When are early diagnoses of MALT lymphoma usually made?
The indolent nature of most MALT lymphomas means that the majority of patients are diagnosed at early stages with relatively nonspecific symptoms.
Is removing the H pylori in asymptomatic individuals recommended to prevent MALT lymphomas?
While the H. pylori infections are associated with this and other gastric disease, the eradication of H pylori in asymptomatic individuals is not currently recommended for prevention of MALT lymphomas or gastric cancer.
What is the occurrence of MALT lymphomas in the general population?
MALT lymphomas occur at a frequency of about 1.5 per 100,000 people per year in the United States and account for about 10% of all non-Hodgkin's lymphomas.
Where in the body does a MALT Lymphoma most commonly occur?
MALT lymphomas are solid tumors that originate from cancerous growth of immune cells that are recruited to secretory tissue such as the gastrointestinal tract, salivary glands, lungs, and the thyroid gland.
What bacteria are MALT lymphomas of the stomach associated with?
In the stomach they are associated, in greater than 90% of all cases, with the bacteria called Helicobacter pylori (H. pylori).
How are MALT lymphomas in the stomach treated?
Those MALT lymphomas that arise in the stomach in response to H. pylori infections are generally successfully treated with antibiotics, which eliminate the bacteria.
What is the best staging area for the evaluation of patients with MALT lymphomas?
it is standard practice that patients presenting with MALT lymphomas should be evaluated in a similar manner to individuals with nodal lymphomas, the more common type of lymphoma that originates at sites within the lymphoid system.
What individuals may be at increased risk to develop MALT lymphomas?
In some cases, such as in the thyroid, MALT lymphomas seem to arise in patients who have autoimmune diseases, which make their immune systems treat their own tissue as foreign or antigenic.
What treatment is effective in those with MALT lymphomas outside the digestive tract?
Effective treatment for these lymphomas has been achieved with local radiation, chemotherapy, and/or interferon.
In what global region is there a higher than average occurrence of MALT lymphomas?
The frequency varies among different populations. For example, in parts of Italy the frequency of MALT lymphomas is as high as 13 per 100,000 people per year.
