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The halfway point between Blountstown, Florida and Little Rock, Arkansas is in Eldridge, Alabama.
Forest City, MO
The halfway point between Tampa, Florida and Manhattan Kansas, falls in or around Nashville, Tennessee.
DeFuniak Spring, Florida is about half way between Tallahassee and Mobile, but it's a little closer to Tallahassee
The halfway point is Rowesville, South Carolina.
Perry, if you take Rte. 19. If you take the interstates, you may as well go to Tallahassee. It's a little more than halfway.
Tallahassee, Florida is roughly halfway. However, the drive is only 12 hours, counting gas and rest stops, so making it in one day should not be a huge problem. But Tallahassee is definitely a good stopping point, little more than halfway and directly on your route.
The closest town to midway between Sanibel Island, Florida and Hilton Head Island, South Carolina is Citra, Florida. The closest large town is Gainesville, Florida but it's a little way off the shortest route.
Oklahoma City is fairly close to halfway between Flint, Michigan and Tucson, Arizona.
Halfway point between little rock and colorado springs
halfway between venice fl and little rock arkasaw
Ashland Ohio is halfway between Little Falls New York & Hopkinsville Kentucky