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What type of brain malformation is lissencephaly?
GaleEncyofNeuroDis
Lissencephaly is part of a spectrum of brain malformations, which are referred to as the agyriapachygyria-band spectrum and are caused by abnormalities in neuronal migration, a critical process in brain development
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What is Type II lissencephaly?
Type II, or "cobblestone" lissencephaly, is characterized by a bumpy appearance of the abnormal surface of the brain. The cortex in Type II lissencephaly is completely abnormal and there are no distinguishable layers
What is type I lissencephaly?
Type I, also known as classical lissencephaly, is distinguished by the smooth surface of the cerebral cortex and an abnormal four-layered cortex. Classical lissencephaly can be associated with abnormalities of the rest of the brain
How common is lissencephaly?
Type I lissencephaly is more common and comprises 43% of lissencephaly syndromes in some studies. Type II lissencephaly accounted for 14% of lissencephalies
When was lissencephaly first described?
Lissencephaly was first described by Owen in 1868 and means "smooth brain," which describes the gross appearance of the brain. Microscopically, the brain appears abnormally thick and disorganized
What is Lissencephaly?
Lissencephaly is a neurological disorder of early brain development that leads to the gross appearance of a smooth brain. The malformed brain lacks the characteristic convolutions of the normal cerebral cortex and is abnormally thick
What are the characteristics of lissencephaly?
In lissencephaly or agyria, neuronal migration fails globally, causing the brain to appear completely smooth and have abnormal layering in the cortex.
What is a Chiari malformation?
Chiari II anomaly-- A structural abnormality of the lower portion of the brain (cerebellum and brain stem) associated with spina bifida. The lower structures of the brain are crowded and may be forced into the foramen magnum.
What is an Arnold-Chiari malformation?
An Arnold-Chiari malformation is an alternative name for a Chiari malformation, a malformation of the brain consisting of a downward displacement of the cerebellar tonsils through the foramen magnum.
Is arteriovenous malformation one of the causes of schizophrenia?
Arteriovenous malformation is not one of the causes of schizophrenia. Arteriovenous malformation affects the heart and blood vessels, not the brain.
What is Arnold-Chairi malformation?
Arnold-Chiari malformation is a rare genetic disorder in which parts of the brain are formed abnormally. Malformations may occur in the lower portion of the brain (cerebellum ) or in the brain stem.
What is karie malformation?
The closest match for karie malformation is Chiari malformation. When the brain tissue spreads down into a person's spinal cord, this is called Chiari malformation. Treatment is available, but is not needed in some cases.
What is kary?
The closest match for karie malformation is Chiari malformation. When the brain tissue spreads down into a person's spinal cord, this is called Chiari malformation. Treatment is available, but is not needed in some cases.
