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This called synaptic transmission. An overview of how this takes place is explained underneath.

1. Action potential (nerve impulse) reaches the synapse of the neurone sending the message (pre-synapse).

2. Calcium channels open in pre-synapse, allowing calcium into cell.

3. Calcium allows vesicles (little "bubbles" filled with neurotransmiiter) to bind to the cell membrane.

4. Membrane directly attached to vesicles opens up, allowing neurotransmitter release without allowing anything else in/out of the cell.

5. Neurotransmitter chemicals (e.g. Glutamate) travel across synaptic cleft (gap between 2 synapses) to the synapse of the neurone receiving the message (post-synapse).

6. Neurotransmitter binds to it's specific receptor on the outer membrane of the post-synapse (in glutamate's case, NMDA or AMPA receptors), activating the receptor.

7. Activated receptors open sodium ion channels in the post-synapse, allowing sodium into post-synapse (this is just one outcome, there are hundreds of neurotransmitters and receptors and as many unique responses. Some are excitatory, causing action potential propagation in the neurone, some inhibitory, stopping action potential propagation).

8. The sodium influx depolarises the post-synapse (brings the negative voltage of the cell closer to 0mV).

9. This depolarisation propagates an action potential which travels down the neurone axon towards the next neurone.

10. When the action potential reaches the synapse the process begins again.

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