influenza
Edward Cullen formerly Edward Masen was dying of the Spanish Influenza when Carlise Cullen found him in a ward with the dying and changed him into a vampire
Spanis Influenza
It was the Influenza flu epidemic (Spanish Influenza, for you non spanish speaking peeps)
Edward Cullen is a Vampire because Carlisle Cullen changed edward because Carlise grew attached to him in hospital when Edward was dying of Spanish Influenzia. So Carlise took him back to his home and changed Edward. Hope that answers your Question.
A disease called Spanish Influenza.
He was changed into a vampire in a hospital in Chicago, Illinois. He was dying of the Spanish influenza and Carlisle saved him in 1918.
Edward was dying of the Spanish Influenza when Carlisle found him.
Edward was changed in a hospital in Chicago dying of Spanish influenza in 1918. Carlisle found him there and changed him.
Edward Cullen was changed into a vampire by Carlisle Cullen when Edward was 17. he and his mother had spanish influensa and were both dying. Carlisle was with Edwards mother, just before she died she told Carlisle to save edward, in a way no one else could, carlisle thought she knew he was a vampire but before he could ask she was dead. So edward had no one in the world at all, he was dying and carlisle had no companion. so carlisle changed him into a vampire witch is very very very hard.
Of smallpoks
I think he was changed sometime between 1901-1907. Both his parents died from the influenza outbreak and he was dying too so Carlisle changed him. Since Edward was sick and in the hospital Carisle probably changed him right there.
Edward was dying of the Spanish influenza in the 1920's and so was his mother. His mother was so close to dying herself that she told Carlisle "you must do everything in your power to save my boy." and obviously she knew his secret. So Carlisle changed him and now he's a vampire. Yes so that it how Edward Cullen became a vampire, good job Carlisle!