no atleast i do not think so
The Justinian plague affected the Roman Empire from 541-542 AD. The Bubonic plague or the black death name was not used by that time but historians are sure that it is the same thing.
The Bubonic Plague (also known as the Black Plague) caused death throughout Enlgand around the time of 932 A.D.
a long time ago
the great plague
The Black Death, a deadly bubonic plague caused by the bacterium Yersinia pestis, swept through Europe in the 14th century, resulting in the deaths of an estimated 25 million people, roughly one-third of the population at that time.
The motto of Shakespeare Institute is 'Per Ardua Ad Alta'.
The Antonine Plague was an ancient pandemic that affected the Roman Empire around 165-180 AD, during the reign of Emperor Marcus Aurelius. It is believed to have been either smallpox or measles, causing widespread illness and death.
there is great significance is any species of mouse and by extension rat. this is because they are a vital part of the food chain, they keep the populations of insects etc regulated and they themselves feed predators higher up in the food chain such as foxes and birds of prey. They are also great carriers of disease. the bubonic plague, which wiped out a major chunk of englands population around 1340-50 ad, the plague was carried by rats and mice which got into every home and food store spread the plague like wildfire.
Shakespeare was born in 1564 AD.
The black death or bubonic plague originated in the asian plains and traveled in fleas that lived on rats that were regular passengers on ships. The plaque really started take effect and show up around AD 1346 in Crimea. The plaque reached its peak amount of deaths in Europe. The death count was about 75-200 million or 30%-60% of Europe's total population.
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deterioration of Rome, Black Plague, Crusades, and a lot of killing and Poverty... In Europe at least