Leonardo da vinci may not have been the first, but probably the most famous.
Michelangelo.
Filippo Brunelleschi
Mechelangaelo was an Italian renaissance painter, sculptor, engineer, architect, and poet.
By reviving a classical Roman-style dome
With out a time frame in this question there are two from the Renaissance, da Vinci and Michelangelo.
The architect Pei's first name is Ieoh
The first known architect in history was Imhotep of Egypt
Michelangelo was an Italian Renaissance painter, architect, sculptor, engineer, and poet. His style is now incorporated historically with works from that period and many propose that he was the pinnacle of all artistic achievement of the Renaissance.
He was a Florentine sculptor during the Renaissance. Of course he was, but his real influence was as an architect.
Michelangelo
The Renaissance metalworker who designed the doors for the Baptistry was Lorenzo Ghiberti. He was also a well-known architect and forged the doors from bronze.
Giorgio Vasari, an Italian painter and architect, is often credited as the humanist scholar who first identified and defined the Renaissance in his work "The Lives of the Most Excellent Painters, Sculptors, and Architects," published in 1550. He recognized the rebirth of classical art and culture during the period as a defining characteristic of the Renaissance.