What were the difficulties involved in building the panama canal?

The biggest problem was disease and until the mosquitoe was taken care

of, progress on the canal couldn't move forward.

it took them 10 years to build the Panama Canal.

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Also, the Panama Isthmus is a high ridge. The first attempt, by the French civil engineer de Lesseps, was at sea-level in the way he had successfully designed the Suez Canal; but failed due to the sheer difficulty and cost of cutting through the hill rather than using locks and feeder-rivers.