actin filaments
actin
During muscle contraction, myosin cross bridges attach to active sites of ACTIN FILAMENTS.
actin (thin) filaments
During skeletal muscle contraction myosin cross bridges attach to active sites of actin filaments. Actin filaments bind ATP. Their growth is regulated by thymosin and profilin.
Myosin functions as an ATPase utilizing ATP to produce a molecular conformational change of part of the myosin and produces movement. Movement of the filaments over each other happens when the globular heads protruding from myosin filaments attach and interact with actin filaments to form crossbridges. The myosin heads tilt and drag along the actin filament a small distance (10-12 nm). The heads then release the actin filament and adopt their original conformation.
1. Muscles fibers with a large diameter develop more force, and have more myofibrils and more myosin heads that can attach to actin. The amount of force is dependent on the number of myosin heads attached to actin.
Actin and myosin
Actin Filaments
Actin is a contractile protein fibers present in muscles.It occurs in two forms a.monomeric G actin b. polymeric F ACTIN.
Actin was discovered by Straub in 1942.
Actin