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Chromosome Disorder
Down syndrome is a chromosomal disorder. It is caused by having 1 extra chromosome (chromosome 21).
Down Syndrome is a trisomy of the 21st chromosome as opposed to an allelic inheritance through the X chromosome. Trisomy is a somatic disorder caused by improper division during gametogenesis (usually of the ovum) that results in 3 copies of the 21st chromosome in the egg once it is fertilized.
Sex-linked disorders are passed on the X chromosome. The man supplies the Y chromosome to his sons so the disorder cannot be passed on to the sons. But the man gives his daughter an X chromosome so the disorder can be passed on to her.
Sickle cell disease is an autosomal reccessive sexlinked trait so, a female msut have 2 recessive alleles to have the trait and a male needs only one allele (this is because there is no corresponding site for this allele on the Y chromosome. The female can be a carrier of the disorder with the defective allele on one X chromosome and a normal allele on the other X chromosome. Female carrriers can have a mixture of normal and abnormal redblood cells.
Yes
The allele that is responsible of Fabry Disorder/Disease is located on the X chromosome and is the only lipid storage disorder identified as being sex linked.
Sounds like the disorder is genetic and located in his x-chromosome.
Sounds like the disorder is genetic and located in his x-chromosome.
Additional chromosome
Males are most likely to have the disorder.
Chromosome map tells us about the deletion or insertion or a part of chromosome that is missed which may be a cause to any disorder.