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There are a number of different kinds of leukemia, and they may have different causes. What is clear is that the causes of leukemia are unclear. There are some good arguments made for increased risk of leukemia based on genetic predisposition(it "runs in your family"), some viruses, exposure to some kinds of chemicals and also exposure to ionizing radiation, either natural or artificial. Leukemia is a not-so-nice form of lymphoma (cancer), and we're still on the trail in an attempt to nail down actual causes. A link is provided to the Wikipedia article on leukemia.
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