Kyshtym disaster happened in 1957.
Kyshtym was created in 1757.
I don't know that there is a technical definition of a nuclear disaster. There are two accidents that are commonly referred to as disasters. One is the well known Chernobyl disaster, and the other is the Kyshtym disaster, both of which were in the former USSR. The Windscale fire, Three Mile Island Accident, and other problems are referred to as accidents. There is an International Nuclear Event Scale, which rates events on a scale of 1 (least important) to 7 (most important). On this scale, the Chernobyl Disaster is rated at a 7, and the Kyshtym Disaster is rated at 6. Three Mile Island Accident is rated at 5, as is the Windscale Fire, and two other accidents. There is a link below to an article on the International Nuclear Event Scale.
A disaster can happen at any time. The trigger depends on the kind of disaster.
Eyemouth disaster happened in 1881.
Luzhniki disaster happened in 1982.
Ibrox disaster happened in 1971.
Knockshinnoch Disaster happened in 1950.
Marchioness disaster happened in 1989.
HaBonim disaster happened in 1985.
Doñana disaster happened in 1998.
Westfield disaster happened in 1871.
Bocholt Disaster happened in 1895.