DNA is never visible to a naked eye but you can see chromosomes filled with DNA in mitosis during prophase.
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prophase
Daughter Chromosomes
Chromosomes become visible (under a microscope) during prophase. At other times DNA is generally difficult to see.
The DNA needed to be stained with a dye, such as ethidium bromide or SYBR Green, that binds to the DNA molecules and fluoresces under ultraviolet light. This allows the DNA to become visible when viewed under a UV transilluminator or gel documentation system.
Isopropyl alcohol can cause DNA strands to precipitate out of a solution, essentially forming a visible clump of genetic material. This property is used in DNA extraction techniques to isolate DNA from a sample by adding isopropyl alcohol to the solution, causing the DNA to become visible and separate from other cellular components.
DNA in cell lysate can be made visible through various techniques such as agarose gel electrophoresis or polymerase chain reaction (PCR). In agarose gel electrophoresis, DNA is separated based on size and can be visualized using a DNA stain under UV light. In PCR, specific DNA fragments are amplified and visualized using gel electrophoresis.
Cold alcohol is used in DNA extraction to precipitate the DNA molecules out of the solution. The cold temperature helps the DNA molecules to clump together and become visible, making it easier to separate them from the rest of the solution.
Chromosomes, which consist of DNA and proteins, are only visible when a cell is preparing to divide. These structures condense and become visible under a microscope during cell division, allowing for the precise distribution of genetic material to daughter cells.
During prophase, the DNA condenses into tightly coiled structures called chromosomes, making them highly visible under a microscope. This condensation allows for easier segregation of genetic material during cell division.
During prophase of mitosis, DNA condenses and coils into visible chromosomes. This phase marks the beginning of the cell division process, where chromosomes pair up and become more distinguishable under a microscope.
DNA photolyase