When the amount of water passed in the urine exceeds the patient's ability to drink ample replacement water, the patient may begin to suffer from symptoms of dehydration
Diabetes insipidus refers to tasteless urine. I can't claim any personal knowledge of the taste of urine in a patient with diabetes insipidus.
Because the pituitary gland is in the brain.
The symptoms suggest diabetes mellitus, specifically diabetes insipidus. This condition is characterized by excessive thirst (polydipsia), excessive urination (polyuria), and normal or high blood sugar levels. The normal ADH levels suggest a possible diagnosis of central diabetes insipidus, which is caused by a deficiency of vasopressin (ADH) production in the brain.
Diabetes comes from the Greek word for "siphon". An Ancient Greek physician noticed that patients with diabetes excessively urinated, "siphoning" fluid out of their bodies. As a result, he named the condition diabetes. The full name is actually diabetes mellitus - mellitus is Latin for "honey-sweet", since the patient's urine was noticeably sweet. There is an unrelated condition, diabetes insipidus, that causes excessive urine as well -- but that urine is very dilute and has no taste.
This sounds like it may be diabetes insipidus. This means that the pituitary gland is releasing too little ADH (antidiuretic hormone). This will cause the kidneys to filter out too much water from the blood, causing very dilute frequent urination, dehydration, hemoconcentration, electrolyte imbalances and possibly heart dysrhythmia.
The early symptoms of any kidney disease can be vary from patient to patient. The most common kidney condition is diabetes. The general symptoms can include swelling of feet, high cholesterol and triglycerides.
During radiation therapy for a brain tumor the hypothalamic-pituitary unit often receives significant doses of radiation with the tendency to develop long-term radiation-induced hypopituitarism (RIH) and its sequelae. The posterior portion of the pituitary gland regulates kidney function through the production of ADH, antidiuretic Hormone, which helps the regulation of water balance. If the pituitary fails to produce ADH, the patient will develop diabetes insipidus.
Only the symptoms of each patient can be treated. Fluids are given to decrease dehydration and medications are given to decrease fever and pain.
dehydration
DefinitionCentral diabetes insipidus is a rare condition that involves extreme thirst and excessive urination.See also: Diabetes insipidus - nephrogenicAlternative NamesCentral diabetes insipidusCauses, incidence, and risk factorsCentral diabetes insipidus occurs when the body has too little of the hormone vasopressin.Vasopressin limits the amount of urine the body produces. Normally, the hypothalamus gland in the brain makes vasopressin, and the pituitary gland stores the hormone. Without vasopressin, the kidneys do not work properly to keep enough water in the body. The result is a rapid loss of water from the body in the form of dilute urine. A person with diabetes insipidus needs to drink large quantities of water, driven by extreme thirst, to make up for this excessive water loss in the urine (as much as 20 liters per day).The reduced levels of vasopressin associated with central diabetes insipidus may be caused by damage to the hypothalamus or pituitary gland. This damage may be related to surgery, infection, inflammation, tumor, or injury to the head.Sometimes the cause remains unknown. Very rarely, central diabetes insipidus can be caused by a genetic defect.SymptomsIncreased amount of urine productionExcessive thirstConfusion and changes in consciousness due to dehydration (if the patient is unable to drink)Signs and testsA person with central diabetes insipidus produces more than 3 liters of urine a day. Urinalysis will show a low concentration of salt in the urine.A water restriction test is used to look at how well the kidney works and how much urine is produced. This test is done during a hospital stay. A weight check, urine collection, and a blood test to check sodium concentration are done every hour. The blood sodium concentration may become high if the condition is untreated, and a person is not allowed to drink water.A CT or MRI of the head may show a problem in or near the pituitary gland.A person with central diabetes insipidus produces more than 3 liters of urine a day. Urinalysis will show a dilute urine with a low concentration of salt in the urine.TreatmentThe cause of the underlying condition should be treated.Vasopressin (desmopressin) may be given either as a nasal spray, tablets by mouth, or injections under the skin. This controls the urine output and fluid balance and prevents dehydration.In mild cases, drinking more water may be all that is needed. If the thirst mechanism is not working (for example, if the hypothalamus is damaged), a prescription for a certain amount of water intake may also be needed (usually 2 - 2.5 liters per day) to ensure proper hydration.Expectations (prognosis)The outcome depends on the underlying disorder. If treated, central diabetes insipidus does not cause severe problems or result in early death.ComplicationsDehydrationElectrolyteimbalanceConfusion and changes in mental status may develop if the condition is not treated.All patients with diabetes insipidus should wear a medic alert bracelet or necklace to alert caregivers to this condition in an emergency situation.Calling your health care providerCall your health care provider if symptoms indicate diabetes insipidus may be present.PreventionMany of the cases may not be preventable. Prompt treatment of infections, tumors, and injuries may reduce risk.ReferencesVerbalis JG. Posterior pituitary. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 243.
diabetes mellitus
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