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Medicines removed from the body by the kidney are removed at a rate that is related to their blood concentration. When the rate of removal equals the rate of ingestion, the concentration has 'leveled off'. Drugs like Ethanol are dealt with enzymatically by the body. In general, enzymes can be found in the blood, or in the liver. If the rate of ingestion of a substance is greater than the maximum rate that the enzymatic system can dispose of the substance, the concentration will increase without bound.

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16y ago

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