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The crossbridge cycle is the cyclical formation of links between actin and myosin. This results in the sliding of thin filaments towards the M line of a sarcomere. The myosin head undergoes conformation changes which allows it to swivel back and forth. In its low energy form, myosin has a low affinity for actin. The ATP prepares myosin for binding with actin by moving it to its high energy form position. When myosin contracts, it has a high affinity for actin.
myosin crossbridge binding
ATP
The thick filament is composed of the myosin molecule. The thin filament is composed of the actin molecule. Flexing the head of myosin provides the powerstroke.
Myosin makes up the THICK filaments, and actin makes up the thin filaments of myofibrils.
Myosin
Actin Filaments
shortening of the muscle fiber
Myosin. The A band has thick (myosin) and thin (actin) filaments.
Thick Filaments
In thick filaments
Thick - it is the length of myosin.