Per the 2006 Saturn Vue Owner's Manual, it says every 100,000 miles for 'normal' service, every 50,000 miles for 'severe' service.
You do not need to change the transmission fluid in the Saturn vue. It is a sealed system and only needs to be replaced when the trans needs rebuilding.
how do I put transmission fluid in a Saturn vue
How do you check the transmission fluid on a 2003 Saturn vue
Transmission
Only the manual transmission Vue can be flat-towed.
There is no powersteering fluid. It is electronic.
it uses a Delco synthetic transmission fluid on the CVT 4 cylinder transmission and ATF on the V6
no........
How much transmission to replace new?
Yes and I would suggest the sooner the better, no later then 50,000 miles. If it is more then this you will need to do it twice. The first time is to flush it clean. You are looking at $150 - $300 to have this done. The transmission is weak on the Vue.
7.2L
Take it to a Goodwrench certfied shop. The transmission in the Saturn Vue has no dipstick, so requires service by a certified mechanic. Unless you have a leak, which you would obviously see, there is no need to check the fluid level.