Let the River Run was created in 1988.
Run of River Power was created in 2005.
Grizzly River Run was created in 2001.
Thief River Falls Run was created in 1986.
Cooper River Bridge Run was created in 1978.
Let Him Run Wild was created in 1965.
Let the River Flow with Darrell Evans was created in 1997.
Fifth Third River Bank Run was created in 1978.
Let The Blood Run Free was created in 1990.
The Mississippi River defines the eastern border of the state of Missouri, and does not actually run through the state (as the Missouri River does) except where the river has created a few small islands.
"Let the River Run" from Working Girl.
That is the Deisty theory
The River To River Festival was created in 2002.