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There was a Henry lever-action rifle that existed during the Civil War (1860s). It used metallic cartridges (self-contained, with a primer on one end and a bullet in the other). But the real popularity of cartridges in firearms didn't happen until the 1870s. Remember this first generation of cartridge-using firearms were all made for black powder, until smokeless or "nitro" powder got popular around 1900.

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Q: When was the first cartridge firearms made?
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