One could fly from a wide variety of states and countries from the Detroit Metro AIrport. The Detroit metro Airport operates mostly along the eastern coast of the United States.
There are currently no airlines that fly the A-380 into Detroit and (from what I can tell) no plans to in the near future.
Currently, November 2012, they only fly into Detroit.
No, there are no Air Berlin flights that connect at Detroit Metropolitan airport. To get to this airport, you would need to fly through another airport, and take a connecting flight.
The Kisangani Bangoka International Airport is located in Tshopo, Congo. Kenya Airways, Metro Batavia and Express One International are major airlines that fly to this airport.
The best prices from DTW - Detroit Airport to Burbank, CA is usually Delta Airlines.
You can't fly from Seattle to Ann Arbor directly. The closest airport is Detroit Metropolitan Airport, 25-miles away. The trip from Seattle to Detroit takes about 4 to 4 and a half hours.
There is a few airlines that fly Islip Airport. This is a national airport.
Could be LHR (Heathrow) or LGW (Gatwick).
There is only 1 airport in Nice, which Easyjet does fly to.
You could fly into Strasbourg or Stuttgart. Dornstetten is almost midway between the two, about 50 km from each.
You would have to go through another country. You could fly to Charles de Gaulle Airport in France and on to Mali from there.
Jerusalem does not have an airport, so you would have to fly into Ben Gurion Airport in Tel Aviv. From Tel Aviv to Jerusalem is an hour and change depending on traffic. Detroit to Ben Gurion would be 13 hours theoretically if you could get a direct flight. I have never seen such a direct flight, so it would take 13 hours + 1.2 hours + layover time.