From the word bio, Bio means life and logy mean knowledge.
Robert Hooke
Our first actual knowledge of biology came during the renaissance period.
Humans have been looking at and studying biology since they first came into existence. There wasn't ever a specific date, time, place or person who first came up with the idea.
Biology is applied in technology by means of agriculture and also in industry of clothing for example cotton, it is made or came from a plant.
The question is very confusing; please re-think the question and edit it. For example, "knowledge in Biology" either came from the scientific method, or it can at least be addressed using the scientific method. If not, then you are not talking about "knowledge in biology".
Biology
This question regards the earlier theories as to the origins of life. This theory came to be rejected as genetics and the biochemical pathways to life came to be understood through evolutionary biology.
I study biology. Yes, it's a hybrid. However, it didn't came from combination of lime and passion fruit.
Yes, it is. Collecting and collating information is the beginning of all science. Taxonomy came before biology!
The subject of bioethics deals with questions about what people ought to do with their knowledge of Biology.
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When biology papers first came out on the typewriters continuous vertical lines was not possible. Even though computerized technology has gotten much better, biologists continue to eliminate vertical lines.