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Detroit
Ste. Genevieve
Pierre Le Moyne was the first to settle in Mississippi and he establisht a French settlement at Old Biloxi.
New Orleans.
yes
tomnes andew, and iam wrong
it was a better place were they could trade with other colonies.
The oldest city on the Mississippi River is Natchez, Ms (formerly) Fort Rosalie
Jaques Cartier french explorator 1539
The City of New Orleans was founded as a trading community on the shores of the Mississippi River on the land that is currently occupied by the French Market and French Quarter.
1716 as Fort Rosalie, and remains a significant city. Robert Cavelier, Sieur de La Salle he did not find Mississippi, traveled to the mouth of the Mississippi river and claimed for France.
The first European explorers to visit Louisiana came in 1528 when a Spanish expedition led by Panfilo de Narvaes located the mouth of the Mississippi River. The first permanent settlement, Fort Maurepas (at what is now Ocean Springs, Mississippi, near Biloxi), was founded by Pierre Le Moyne d'Iberville, a French military officer from Canada, in 1699. By then the French had also built a small fort at the mouth of the Mississippi at a settlement they named La Balise (or La Balize), "seamark" in French.