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Q: Which checkpoint in the cell cycle is affected by paclitaxel?
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What is the checkpoint that makes the key decision of whether the cell will divide is?

cell cycle checkpoint


The checkpoint that makes the key decision of whether the cell will divide is the checkpoint?

Cell cycle


Where does the checkpoint regulate in the cell cycle?

G1 phase, G2 phase of the cell cycle


What part of the cell cycle results in daughters cells?

G2 checkpoint


What is the G1 checkpoint and where does it fit into the cell cycle?

If the cell gets the go-ahead signal at this checkpoint, it usually completes the whole cell cycle and divides. If it does not receive the go-ahead signal it enters a non-dividing phase called G0 phase.


Before a cell can proceed to mitosis from the gap 2 stage of the cell cycle it must?

it must pass a critical checkpoint.


How are all the cell cycle checkpoints similar?

They give the go-ahead signal to progress to the next checkpoint


Once the checkpoint is passed in the cycles the cell is committed to division?

DNA replication occurs during the S phase of mitosis. Once the checkpoint S is passed in the cell cycle, the cell is committed to division.


What happens at each checkpoint during the cell cycle?

Check for large healthy cell, proper DNA replication, and nuclear cytoplasmic division.


What events of the cell cycle might inhabit general metabolism?

The checkpoint in the stages can inhibit metabolism


What is necessary for a cell to pass the G2 checkpoint?

G1/S checkpoint


Describe the role of checkpoints in the onset of cancer?

Cell cycle checkpoints are used by the cell to monitor and regulate the progress of the cell cycle. Checkpoints prevent cell cycle progression at specific points, allowing verification of necessary phase processes and repair of DNA damage. The cell cannot proceed to the next phase until checkpoint requirements have been met. Several checkpoints are designed to ensure that damaged or incomplete DNA is not passed on to daughter cells. Two main checkpoints exist: the G1/S checkpoint and the G2/M checkpoint. G1/S transition is a rate-limiting step in the cell cycle and is also known as restriction point. An alternative model of the cell cycle response to DNA damage has also been proposed, known as the postreplication checkpoint. p53 plays an important role in triggering the control mechanisms at both G1/S and G2/M checkpoints. Impaired spindle checkpoint function has been found in many forms of cancer. The BRCA1 tumor suppressor plays a role in the activation of human chk1, therefore the posreplication checkpoint may prevent the genetic changes that lead to cancer. Mutations in factors contributing to cell cycle arrest at the restriction point are thought to be the main contributors of cancer. hope this helps!