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Diseases such as Diabetes mellitus and deafness (DAD), Leber's hereditary optic neuropathy (LHON), Leigh syndrome, and Myoneurogenic gastrointestinal encephalopathy (MNGIE) can be considered to be mitochondrial disorders.

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12y ago

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When a woman has Mitochondrial Myopathy can it be passed through her son to his children?

No. Mitochondrial diseases are passed on only by mothers. So, she will pass it to her son. But her son will not be able to pass it to his children, since mitochondrial diseases are passed solely by women. Most (if not all) mitochondrial DNA are of maternal origin.


What is a deadly diseases caused by malfunctioning organelles?

Mitochondrial disease


What has the author Roberto Scatena written?

Roberto Scatena has written: 'Advances in mitochondrial medicine' -- subject(s): Mitochondrial pathology, Mitochondrial Diseases, Effect of drugs on, Cells, Mitochondria, Physiology


Is cystic fibrosis a mitochondrial disease?

No, cystic fibrosis is not a mitochondrial disease. It is an autosomal recessive genetic disorder caused by mutations in the CFTR gene, which is located on chromosome 7. This condition primarily affects the respiratory, digestive, and reproductive systems due to the production of thick, sticky mucus. Mitochondrial diseases, on the other hand, are caused by dysfunctions in the mitochondria, which have their own genetic material separate from nuclear DNA.


Is blindness a disease or a disorder?

Blindness can be caused by many diseases, but is not a disease. Therefore, it is a disorder.


What are two diseases carried in maternal mitochondria?

The two diseases are mitochondrial myopathy and Leber's Hereditary Optic Neuropathy. The first causes weakness and intolerance of exercise & Muscle deteriation. While the second disorder causes sudden blindness when someone is in their 20s or 30s.This was retrieved from Campbell and Rece Biology Book 8th Edition.


What is one reason muscle tissues are likely to be affected by mitochondrial diseases?

Muscle tissues are particularly affected by mitochondrial diseases because they have a high demand for energy due to their continuous contractions and physical activity. Mitochondria are responsible for producing ATP, the energy currency of the cell, and when they are dysfunctional, as seen in mitochondrial diseases, the energy supply to muscle cells is compromised. This can lead to muscle weakness, fatigue, and exercise intolerance, making muscle tissues especially vulnerable to the effects of these diseases.


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How was the identification of nDNA mutations that cause mitochondrial myopathies first made?

first made when a nuclear gene involved in mtDNA replication was found to be defective in a disorder involving a patient with a mitochondrial myopathy


Is crohns disease likely in mitochondrial disease sufferers?

There is no direct link established between mitochondrial diseases and an increased likelihood of Crohn's disease. However, some research suggests that mitochondrial dysfunction may contribute to various gastrointestinal disorders. Individuals with mitochondrial diseases can experience a range of symptoms, including gastrointestinal issues, but these are not necessarily indicative of Crohn's disease specifically. Each condition should be evaluated independently by healthcare professionals.


What pattern of inheritance would lead a geneticist to suspect that an inherited disorder of cell metabolism is due to a defective mitochondrial gene?

The disorder would always be inherited from the mother because the mother's mitochondrial gene is the only one that survives when the zygote is formed. The gamete from the mother contains all the information. The head of the father's sperm is the only part that survives during fertilization. The tail of the sperm containing the male's mitochondria (an their genes) is lost when the zygote begins development. Thus it is only from the mother that the disorder can be inherited.