Best is a judgement and you are the judge.
You can best answer your question by thinking through how the garment or item will be used over the course of its useful life.
You can blend silk with wool when spinning yarn, without reaction.
wool from sheep. silk from silkworms.
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Solo yarn is a type of yarn with a worsted weight blend of silk as well as mohair with just a touch of wool.
Wool is fabric that is made from sheep wool. Its spun and turned into fabric. Silk is made from the cocoons of silk worms. Wool is typically thicker, and silk has more flow.
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A wool blend coat has been designed not to shrink, based on the blend of the wool. However, you could wash the wool coat in hot water with maximum agitation, which affects the wool, but not the blend. Your results would be unpredictable.
a wool blend means that other than wool, there are one or more other fibres/fabrics in with the wool.
Generally lightweight polyester and silk blends, washable.
Silk, rayon and wool are all fibres.
Silk is smoother than wool.
Any wool product is clearly labeled as to its wool content. If it is a blend, the blend percentage and the identification of the blended fibre are clearly stated.