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Which part of the neuromuscular junction is affected by botulinum toxin poisoning?
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How does botulisma serious form of food poisoningcause muscle paralysis?
Botulinum toxin (aka. Botox, produced by the bacteria Clostridium Botulinum) causes paralysis by disrupting exocytosis of acetylcholine into the neuromuscular junction. When a nerve impulse reaches the neuromuscular junction, it normally triggers vesicles storing acetylcholine to fuse with the axonal membrane, releasing its contents into the junction where acetylcholine can trigger an action potential in the muscle fibre. Failure of the vesicle to fuse and release its contents into the junction deprives the muscle of any kind of signal that would cause contraction, thereby paralyzing it.
What is the site where the muscle fiber and nerve fiber meet called?
Well of course they meet at the neuromuscular junction
What is the point of contact between a motor neuron and a skeletal muscle cell called?
This point is often called the neuromuscular junction or motor end plate. ?The neurotransmitter used here is acetylcholine.Many diseases occur with dysfunction at this junction, like Myesthenia Gravis, botulism, or Lambert Eaton Myasthenic Syndrome.
What does ach do at a neuromuscular junction?
ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.
Inhibition of acetylcholinesterase by poisoning blocks neurotransmission at the neuromuscular junction because?
ACh is not degraded, therefore, prolonged depolorization is enforced on the post synaptic memebrane
The junction between a motor neurons axon and the muscle cell membrane is called a neuromuscular junction or a?
The junction between a motor neruon's axon and the muscle cell membrane is called a neuromuscular junction or a myoneuraljunction?
Which neurotransmitter is released at the neuromuscular junction?
ACETYLCHOLINE
Where is clostridium botulinum most likley to be found?
clostridium botulinum is a bacterium which produces a neurotoxin called botulin. the toxic acts on nerve terminals at the neuromuscular junction.
How does the neural signal get across the neuromuscular junction?
a neurotransmitter chemical crosses the junction.
What does the neuromuscular junction connect to?
The nervous system and the muscular system are connected by the neuromuscular junction. The connection is done with synapses between nerve and muscle fibers.
A folded region of the sarcolemma at the neuromuscular junction?
At the neuromuscular junction (or presynaptic end) of the sarcolemma, it is referred to as end plate synapse potential.
Type of junction where a motor neuron and a skeleton muscle cell have contact?
A neuromuscular junction.
