Want this question answered?
Botulinum toxin (aka. Botox, produced by the bacteria Clostridium Botulinum) causes paralysis by disrupting exocytosis of acetylcholine into the neuromuscular junction. When a nerve impulse reaches the neuromuscular junction, it normally triggers vesicles storing acetylcholine to fuse with the axonal membrane, releasing its contents into the junction where acetylcholine can trigger an action potential in the muscle fibre. Failure of the vesicle to fuse and release its contents into the junction deprives the muscle of any kind of signal that would cause contraction, thereby paralyzing it.
Well of course they meet at the neuromuscular junction
ACh (acetylcholine) binds to receptors at the NMJ (neuromuscular junction) to induce contraction of muscle.
This point is often called the neuromuscular junction or motor end plate. ?The neurotransmitter used here is acetylcholine.Many diseases occur with dysfunction at this junction, like Myesthenia Gravis, botulism, or Lambert Eaton Myasthenic Syndrome.
ACh is not degraded, therefore, prolonged depolorization is enforced on the post synaptic memebrane
The junction between a motor neruon's axon and the muscle cell membrane is called a neuromuscular junction or a myoneuraljunction?
a neurotransmitter chemical crosses the junction.
clostridium botulinum is a bacterium which produces a neurotoxin called botulin. the toxic acts on nerve terminals at the neuromuscular junction.
The nervous system and the muscular system are connected by the neuromuscular junction. The connection is done with synapses between nerve and muscle fibers.
At the neuromuscular junction (or presynaptic end) of the sarcolemma, it is referred to as end plate synapse potential.
A neuromuscular junction.