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Hormones (oral contraceptives, menstruation, pregnancy), drugs and dietary factors.

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Q: Which substances can trigger an attack of acute intermittent porphyria?
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Is there anyone that had porphyria?

First of all you must have a family history with porphyria; secondly the type of porphyria in your family must be definitely established as well as the mutation in your family. The porphyrias are a group of diseases (disorders) caused by the over-production of porphyrins, as a result of an inherited metabolic defect. In most cases the defect is genetic, except with one form porphyria cutanea tarda, that is however usually not genetic, but is acquired as a result of certain forms of liver dysfunction.A patient with porphyria have two major symptoms;the acute attack ( severe abdominal pain, nausea, vomiting, constipation, and pain in the back and limbs);and photosensitivity (due to sun-exposed areas, a skin disease develops with blisters and sores, particularly on the face and backs of the hands, forming scars, and healing takes longer than normal.Testing is very problematic and depends on the nature of your symptoms that you experience as well as in what country you live.It must be tested at a PORPHYRIA LABORATORY who are able to perform the complete range of tests necessary as incomplete results may be misleading in giving false-negative results. You have to submit a urine sample and a blood sample at a reputable porphyria laboratory for the following tests;Urine ALA and PBG measurement (this helps to exclude acute intermittent porphyria, and variegate porphyria in the acute attack).Urine porphyrin screening, followed by chromatographic quantitation if positive, to estimate the activity of acute intermittent porphyria and variegate porphyria, and to confirm porphyria cutanea tarda.Plasma fluorescence scan (this helps to exclude several porphyrias, including variegate porphyria and porphyria cutanea tarda).Erythrocyte fluorescence (this helps to exclude erythropoietic protoporphyria and congenital erythropoietic porphyria).DNA testing for the R59W mutation. (this is VP - Variegate Porphyria - South African mutation)If your results are negative, then your symptoms are not due to porphyria, and it is therefore highly unlikely that you in fact have porphyria. Your doctor must in any event help you to find another cause for your symptoms. (Source: Porphyria UCT SA)


What is the disease called where if you see or get sunlight on you you die?

Nothing will cause an instantaneous death in this situation. However, there are certain diseases are aggravated by sunlight. It can trigger an attack in some kinds of porphyria, and in xeroderma pigmentosm the cells can't regenerate themselves after being exposed to sunlight and will invariably cause skin cancers.


Should you drink alcohol after a migraine?

Alcohol is often a Migraine trigger. Drinking it after a Migraine attack may trigger another attack.


What substances or events can trigger an asthma attack?

A lot of mucuss observed broncholoties in the lung cause asthma


Can cat urine trigger asma attack?

yes


Which statements is false regarding how ozone can affect the lungs and respiratory system?

Ozone can trigger Asthma attack in adults but not in children.


What do killer cells attack?

toxic substances


What mounts the attack against particular foreign substances?

The immune system reacts to foreign substances.


Can cheese cause headaches?

Cheese, particularly aged cheese, can trigger migraines. The older the cheese, the more likely it is to trigger an attack.


Can crying a long period of time trigger an asthma attack?

Upto my knowledge, the answer is no.


What are some risk factors when you have asthma?

There are many risk factors which can trigger an asthma attack. Chest infection, air pollution, smog, high pollen count in spring, smoking and emotional outbursts can all trigger an attack.


What substances attack metals stonework and skin?

Corroisive acid