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Q: Which type of mature B cell is most likely to respond to a protein antigen?
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Naiive B cells are lymphocytes that have not yet been exposed to antigen. Once it can identify a particular antigen, it will undergo production of antibodies and become a mature B cell. Mature B cells are split into two categories: plasma B cells and memory B cells. Plasma B cells will continue to produce large amounts of antibodies. Memory B cells are stored so that the next time you encounter the same antigen, it can start producing antibodies much quicker because it remembered from the previous encounter.


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When a B cell detects an antigen, it will engulf it and then display it on its cell surface with an MHC molcule. This antigen/MHC combination is then detected by a T cell - which will send signalling molcules to B cells to multiply and mature into plasma cells (which create antibodies against the antigen) and memory B cells (which 'remember' the antigen for next time).They become plasma cells


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