a black and white hole
The cosmic cube is the same as the teserract. They are both the 2nd most powerful thing in the universe. The most powerful being in the universe would be galactus because he is older than the universe itself and absorbs planets to give him even more power.
He-Man might be the most powerful man in the universe and he definitely has the reputation of being very powerful. Superman is also considered to be one of the most powerful men in the universe, so this is a matter of some debate.
God, who created the universe.
Money is the most powerful thing in the world. Then comes human brain & mind.Another answer:God because He created you and the world. He was the first thing alive before there was anything; now look what He's done, look how far His creation has gone.
Love is the most powerful thing
Hyperstorm
A Super Nova, exploding star, is by far the most destructive thing in the universe.
The only thing that is "most powerful" about them is their gravitational attraction, when you get very close to them.
The spike hammer or the fantastic pilum.
Known Universe - 2009 Most Powerful Stars 3-3 was released on: USA: 19 May 2011
Life
Depends on how you define power. If we take it as transferring energy then it will have to be the most luminous. So the most luminous star known in the Universe is R136a1